
Transforming ALS Diagnosis and Drug Discovery
Breakthrough diagnosis and treatments
—reimagining ALS care with cutting-edge technology.
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About SONoALS
Mission-Driven Science
SONoALS, Inc. is a pioneering startup to redefine how ALS is diagnosed and treated. Our mission is to bring non-invasive, data-rich monitoring to the frontlines of neurodegenerative disease research. The team unites clinical neuroscience and biomedical engineering to make that mission a reality.
Breakthrough Technology
Wearable Ultrasound × AI-Powered Analysis
Revolutionary ultrasound technology combined with AI-powered analysis for Amyotrophic Lateral Sclerosis (ALS) monitoring and diagnosis.

Wearable Ultrasound Device Prototype
- Minimized ultrasound probe via a hub, allowing direct attachment to the skin
- Connectable to a laptop for simultaneous 4-muscle measurement & recording for 20 minutes in a resting state
- Acquired data is sent to the AI analysis server to display results

Overall View
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Probe & Hub Close-up
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Probe Close-up 1
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Probe Close-up 2
詳細を見るApplication & Measurement Images

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詳細を見るPrecision Tools for ALS Research and Beyond
Transforming healthcare through innovative applications in early diagnosis and drug discovery.

Applications
Early and Non-invasive Diagnosis of ALS
- Fasciculations are one of the biomarkers that appear earlier than needle EMG abnormalities.
Drug Discovery Support
Fasciculation biomarkers responding in days
- Pre-clinical drug screening in humans
- Selection of responder groups
- Significant reduction in clinical trial duration
- Personalized medicine
We aim to realize these goals.
News & Press
Latest updates and achievements from SONoALS
Interview article published in Kei-Do
An interview with CEO Saeki has been published in Kei-Do, a media platform for business leaders, covering the origins and future vision of SONoALS' ALS early diagnosis and clinical trial support
Spoke at MedTech Angels Season 5 Demo Day
CEO Saeki joined the "Season 4 Alumni's One Year" panel as the Season 4 Grand Prize Winner at the Demo Day, held at Nihonbashi Life Science Hub (hybrid event)
Pitched at NQ Health Accelerator Demo Day
Pitched as one of the 16 selected startups at the Demo Day held at Nakanoshima Qross Qrossover Lounge "Yume"
Get in Touch
Ready to learn more about our revolutionary ALS technology? Let's connect.
Company Information
Address
WALLSQUARE Kitanozaka
2-13-15 Yamamoto Ave., Chuo Ward
Kobe City, Hyogo 650-0003, Japan
Established
May 2025


Tadashi Kojima
CTO/COO, SONoALS